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ey0018.11-15 | New insight into preconceptional and prenatal programming | ESPEYB18

11.15. Sex-specific programming effects of parental obesity in pre-implantation embryonic development

K Hedegger , J Philippou-Massier , S Krebs , H Blum , S Kunzelmann , K Forstemann , M Gimpfl , AA Roscher , R Ensenauer , E Wolf , M Dahlhoff

Int J Obes (Lond). 2020 May;44(5):1185–1190. https://pubmed.ncbi.nlm.nih.gov/31776435/These authors investigated the effect of maternal and paternal obesity on gene expression level in the mouse blastocyst. Firstly, they show that female and male offspring were differentially sensitive to an obesogenic maternal environment in the early phase of preimplantation. Male blastocysts from o...

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ey0016.15-6 | (1) | ESPEYB16

15.6. Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother-child cohort study

D Gomes , R von Kries , M Delius , U Mansmann , M Nast , M Stubert , L Langhammer , NA Haas , H Netz , V Obermeier , S Kuhle , LM Holdt , D Teupser , U Hasbargen , AA Roscher , R Ensenauer

To read the full abstract: PLoS Med 2018;15:e1002681.These authors highlight a novel pregnancy risk factor, late-pregnancy dysglycaemia in women who are obese but had normal glucose tolerance when they were tested for gestational diabetes mellitus (GDM) earlier in pregnancy. In a prospective cohort study of obese women without GDM (n<...

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ESPE Yearbook of Paediatric Endocrinology

11.15. Sex-specific programming effects of parental obesity in pre-implantation embryonic development

15.6. Late-pregnancy dysglycemia in obese pregnancies after negative testing for gestational diabetes and risk of future childhood overweight: An interim analysis from a longitudinal mother-child cohort study

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